Methionine is an
essential amino acid and important in angiogenesis, the growth of new blood vessels
Overconsumption of methionine,[4] the methyl
group donor in DNA methylation, is related to cancer growth in a number of
studies.[5][6][7]Methionine was
first isolated in 1921 by John Howard Mueller.[8]
High methionine foods
include nuts, beef, lamb, cheese, turkey, pork, fish, shellfish, soy, eggs,
dairy, and beans.
Methionine restricted diet and high
dose selenium:
Methionine restriction sensitizes
cancer cells to sodium selenite by lowering glutathione which increases
oxidative stress.
Cancer cells are highly dependent on
several different amino acids for growth and cell division. Cancer cells are
universally dependent on methionine
It is both practical and effective to
limit the dietary intake of methionine as a means to starve cancer cells of
this essential nutrient. Normal cells are unharmed by short
term limitation of methionine
Methionine restriction is very powerful
and may be sufficient as a standalone therapy for many early stage cancers . Click hereto
read an article on dietary methionine restriction published in 2001 by Dr
Epner.
A methionine restricted diet may be
continuous or cycled on and off depending on individual circumstances
Methionine
restriction involves the elimination of many foods and a focus on mostly fruits
The
natural sugars in fruits will not feed cancer cells or cause tumors to grow. It
is a common misconception that fruit equals sugar and that fruits raise blood
sugar. Fruit can be a problem if there is a high fat intake (greater than 10%
of total caloric intake) which will cause insulin resistance.
High Dose Selenium:
Selenium is an essential trace element
found in foods and nutritional supplements. Studies have shown that
selenium not only can prevent cancer but can also treat it.
Sodium
selenite is the most effective form of selenium for therapeutic use.
Cancer cells are triggered to self destruct (apoptosis) when exposed to
sodium selenite at low concentrations. Normal healthy cells are unharmed
unlike treatment
Genipin:
Genipin
is a compound present in gardenia fruit extract (Zhi Zi) that has been found to
inhibit a mitochondrial protein called UCP2. Genipin has been shown to
trigger apoptosis through the generation of excess reactive oxygen species
(ROS) by increasing the level of ATP generated by mitochondria. UCP2
maintains the cancer cell at a low level of oxidative stress by keeping
the level of mitochondrial oxidative phosphorylation minimized. Gardenia
fruit extract (Zhi Zi) has been used in traditional Chinese medicine for
thousands of years. Current scientific studies are demonstrating potent and
selective anti-tumor activity.
Vitamin E Succinate
The
semi-synthetic form of vitamin E, vitamin E succinate (VES) has been
extensively studied as a cancer preventative and chemotherapeutic agent.
VES
reacts directly with mitochondrial complex II generating ROS and has been shown
to trigger apoptosis in over 90% of cancer cell types. VES is completely
nontoxic to normal cells.
Source Nutritional Oncology
Research Institute
